I'm considering getting one because I would like to seperate my home address to a business address. I might move from home to home.

Does anyone here had an experience and knowledge regarding a P.O. box?

Yes, I rent one. They come in all sizes, so drop by your local post office to see what each size means in practice. Be sure to choose the right size. If you want to get a bigger one later, that means a different box number, which is a different address, which means delays due to address forwarding. For a small box, I pay about US$50/year.

Some stores (e.g., the old MailBoxes Etc.) offer PO boxes. I didn't use them because you don't get the 24-hour access you do from a US post office. You should check with the Canadian post offices to see what access they provide.

I hope this helps.

Yes, that is the tricky part Steve. If you rent a PO box from the post office, you can get access 24/7, but if you really want to separate your home and office addresses, then something like mailboxes etc would be better. They can sign for your overnight packages. If you don't do that, then you still have to give your home address to anyone wanting to overnight you something, so at that point you might as well keep it all the same.

We use one because there's no mail delivery to our home or store. We rent a small box and if there's overflow we pick it up at the counter. We thought about getting a bigger box but we'd have to change box numbers and that's not worth it right now.

This is an excellent point. I never receive packages overnight so it's not been an issue for me. For others, it's an important consideration.

We use a Mailboxes Etc. type place. UPS and FedEx won't deliver to a PO Box, but they will to these places. Since we receive deliveries a couple of times a week, it was the obvious choice for us. Most of our deliveries come in large boxes, so we have a medium sized box, and they hold the larger packages for us.

I rent a unit through The UPS store, and to date, (2 yrs) have been extremely happy with it. I occasionaly will get deliveries at home still also. But what i find important is the anonimity of my location to my customers. (Im an E-commerce)